Description
Product Characteristics:
Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.
Subcellular location: Cell membrane
Synonyms: C79158, FLJ21897, FLJ31917, SPRE2_HUMAN, MGC163164, Spred 2, Sprouty protein with EVH 1 domain 2 related sequence, sprouty related EVH1 domain containing 2, Sprouty related protein with EVH 1 domain 2, zgc:77284.
Target Information: SPRED2 is a member of the Sprouty (see SPRY1\, MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1\, MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM, Mar 2008]